Article
G protein-coupled receptor signaling through Gq and JNK negatively regulates neural progenitor cell migration.
Proceedings of the National Academy of Sciences of the United States of America - 30 Aug 2005
Mizuno Norikazu, Kokubu Hiroshi, Sato Maiko, Nishimura Akiyuki, Yamauchi Junji, Kurose Hitoshi, Itoh Hiroshi
Abstract excerpt
In the early development of the central nervous system, neural progenitor cells divide in an asymmetric manner and migrate along the radial glia cells. The radial migration is an important process for the proper lamination of the cerebral cortex. Recently, a new mode of the radial migration was found at the intermediate zone where the neural progenitor cells become multipolar and reduce the migration rate....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.