Article
Efficient inference of haplotypes from genotypes on a large animal pedigree.
Genetics - 1 Mar 2006
Baruch Eyal, Weller Joel Ira, Cohen-Zinder Miri, Ron Micha, Seroussi Eyal
Abstract excerpt
We present a simple algorithm for reconstruction of haplotypes from a sample of multilocus genotypes. The algorithm is aimed specifically for analysis of very large pedigrees for small chromosomal segments, where recombination frequency within the chromosomal segment can be assumed to be zero. The algorithm was tested both on simulated pedigrees of 155 individuals in a family structure of three generations and on...
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