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Article

The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings.

Genes & development - 15 Dec 2005

Ronshaugen Matthew, Biemar Frédéric, Piel Jessica, Levine Mike, Lai Eric C

Abstract excerpt

The Drosophila Bithorax Complex encodes three well-characterized homeodomain proteins that direct segment identity, as well as several noncoding RNAs of unknown function. Here, we analyze the iab-4 locus, which produces the microRNAs iab-4-5p and iab-4-3p. iab-4 is analogous to miR-196 in vertebrate Hox clusters. Previous studies demonstrate that miR-196 interacts with the Hoxb8 3' untranslated region. Evidence...

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Identifiers

PMID: 16357215
DOI: 10.1101/gad.1372505
PMCID: PMC1315399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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