Analysis of maxillopedia expression pattern and larval cuticular phenotype in wild-type and mutant tribolium.

doi:10.1093/genetics/155.2.721

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Article

Analysis of maxillopedia expression pattern and larval cuticular phenotype in wild-type and mutant tribolium.

Genetics - 1 Jun 2000

Shippy T D, Guo J, Brown S J, Beeman R W, Denell R E

Abstract excerpt

The Tribolium castaneum homeotic gene maxillopedia (mxp) is the ortholog of Drosophila proboscipedia (pb). Here we describe and classify available mxp alleles. Larvae lacking all mxp function die soon after hatching, exhibiting strong transformations of maxillary and labial palps to legs. Hypomorphic mxp alleles produce less severe transformations to leg. RNA interference with maxillopedia double-stranded RNA...

Topics

Alleles
Animals
In Situ Hybridization
Insect Proteins
Larva
Mutation
Phenotype
Tribolium

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Identifiers

PMID: 10835394
DOI: 10.1093/genetics/155.2.721
PMCID: PMC1461110

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