Article
Negative regulation of dorsoventral signaling by the homeotic gene Ultrabithorax during haltere development in Drosophila.
Developmental biology - 15 Aug 1999
Shashidhara L S, Agrawal N, Bajpai R, Bharathi V, Sinha P
Abstract excerpt
Growth and patterning during Drosophila wing development are mediated by signaling from its dorsoventral (D/V) organizer. In the metathorax, wing development is essentially suppressed by the homeotic selector gene Ultrabithorax (Ubx) to mediate development of a pair of tiny balancing organs, the halteres. Here we show that expression of Ubx in the haltere D/V boundary down-regulates its D/V organizer signaling...
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