Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice.

Neuroscience letters - 6 Mar 2006

Koh Seong-Ho, Lee Sang Mok, Kim Hyun Young, Lee Kyu-Yong, Lee Young Joo, Kim Hee-Tae, Kim Juhan, Kim Myung-Ho, Hwang Myung Sil, Song Chiwon, Yang Ki-Wha, Lee Kwang Woo, Kim Seung Hyun, Kim Ok-Hee

Abstract excerpt

Epigallocatechin gallate (EGCG) is a constituent of green tea, and increasing evidence suggests that EGCG has neuroprotective effects on oxidative stress-injured neuronal cells, especially motoneurons. Although the neuroprotective effects of EGCG have been demonstrated in Parkinson's and Alzheimer's diseases and ischemic stroke models, there has been no report on the effect of EGCG on an in vivo model of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caspase 3
Share to Caspases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Catechin

Share to Glycogen Synthase Kinase 3

Share to Glycogen Synthase Kinase 3 beta

Share to Neuroprotective Agents

Share to Spinal Cord

Share to Superoxide Dismutase-1

Source

Identifiers

PMID: 16356650
DOI: 10.1016/j.neulet.2005.10.056

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice.PMID 16356650Read ↗

Epigallocatechin gallate prevents oxidative-stress-induced death of mutant Cu/Zn-superoxide dismutase (G93A) motoneuron cells by alteration of cell survival and death signals.Semantic proximity Read ↗

DJ-1 knockout augments disease severity and shortens survival in a mouse model of ALS.Semantic proximity Read ↗

Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo.Semantic proximity Read ↗

Effect of rosmarinic acid in motor dysfunction and life span in a mouse model of familial amyotrophic lateral sclerosis.Semantic proximity Read ↗

Nicotinamide Riboside and Pterostilbene Cooperatively Delay Motor Neuron Failure in ALS SOD1G93A Mice.Semantic proximity Read ↗

Oxidative stress in ALS: key role in motor neuron injury and therapeutic target.Semantic proximity Read ↗

N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis.Semantic proximity Read ↗

Bromocriptine methylate suppresses glial inflammation and moderates disease progression in a mouse model of amyotrophic lateral sclerosis.Semantic proximity Read ↗

The Chinese prescription Wen-Pi-Tang extract delays disease onset in amyotrophic lateral sclerosis model mice while attenuating the activation of glial cells in the spinal cord.Semantic proximity Read ↗

L-carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis.Semantic proximity Read ↗

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model.Semantic proximity Read ↗

Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.