Article
STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2006
Rodriguez Moses, Zoecklein Laurie, Gamez Jeffrey D, Pavelko Kevin D, Papke Louisa M, Nakane Shunya, Howe Charles, Radhakrishnan Suresh, Hansen Michael J, David Chella S, Warrington Arthur E, Pease Larry R
Abstract excerpt
Epidemiological studies suggest that an environmental factor (possibly a virus) acquired early in life may trigger multiple sclerosis (MS). The virus may remain dormant in the central nervous system but then becomes activated in adulthood. All existing models of MS are characterized by inflammation or demyelination that follows days after virus infection or antigen inoculation. While investigating the role of...
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