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Article

Targeted calretinin expression in granule cells of calretinin-null mice restores normal cerebellar functions.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2006

Bearzatto Bertrand, Servais Laurent, Roussel Céline, Gall David, Baba-Aïssa Fawzia, Schurmans Stéphane, de Kerchove d'Exaerde Alban, Cheron Guy, Schiffmann Serge N

Abstract excerpt

Ca2 binding proteins such as calretinin, characterized by the presence of EF-hand motifs that bind Ca2+ ions, are involved in the shaping of intraneuronal Ca2+ fluxes. In the cerebellar cortex, information processing tightly relies on variations in intracellular Ca2+ concentration in Purkinje and granule cells. Calretinin-deficient (Cr-/-) mice present motor discoordination, suggesting cellular and network...

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PMID: 16352645
DOI: 10.1096/fj.05-3785fje

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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