On the identification of differentially expressed genes: improving the generalized F-statistics for Affymetrix microarray gene expression data.

Abstract excerpt

It has been shown that the generalized F-statistics can give satisfactory performances in identifying differentially expressed genes with microarray data. However, for some complex diseases, it is still possible to identify a high proportion of false positives because of the modest differential expressions of disease related genes and the systematic noises of microarrays. The main purpose of this study is to...

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