Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD.

Gastroenterology - 1 Dec 2005

Vermeire Séverine, Pierik Marie, Hlavaty Tibor, Claessens Greet, van Schuerbeeck Nele, Joossens Sofie, Ferrante Marc, Henckaerts Liesbet, Bueno de Mesquita Mirjam, Vlietinck Robert, Rutgeerts Paul

Abstract excerpt

BACKGROUND & AIMS: Three years after the identification of NOD2/CARD15, 2 more genes for inflammatory bowel diseases (IBDs) were reported. The carnitine/organic cation transporter (OCTN) on 5q31 (IBD5) is associated with Crohn's disease (CD) and DLG5 (10q23), a member of membrane-associated guanylate kinase (MAGUK) family, with IBD. We studied mutation prevalence, assessed phenotypic expression, and performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colitis, Ulcerative

Share to Crohn Disease

Share to Disease Susceptibility

Share to DNA Mutational Analysis

Share to Haplotypes

Share to Organic Cation Transport Proteins

Source

Identifiers

PMID: 16344053
DOI: 10.1053/j.gastro.2005.10.006

Genes

DLG5
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD.PMID 16344053Read ↗

Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis.Semantic proximity Read ↗

Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.Semantic proximity Read ↗

Functional variants of OCTN cation transporter genes are associated with Crohn disease.Semantic proximity Read ↗

The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease.Semantic proximity Read ↗

Evidence for association of OCTN genes and IBD5 with ulcerative colitis.Semantic proximity Read ↗

Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.Semantic proximity Read ↗

Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease.Semantic proximity Read ↗

Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31.Semantic proximity Read ↗

Role of CARD15, DLG5 and OCTN genes polymorphisms in children with inflammatory bowel diseases.Semantic proximity Read ↗

A third human carnitine/organic cation transporter (OCTN3) as a candidate for the 5q31 Crohn’s disease locus (IBD5)Semantic proximity Read ↗

Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease.Semantic proximity Read ↗

A risk haplotype in the Solute Carrier Family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.