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Article

Multiple endocrine neoplasia type 2 and the RET protooncogene: from bedside to bench to bedside.

Molecular and cellular endocrinology - 9 Mar 2006

Machens Andreas, Dralle Henning

Abstract excerpt

Although the initial characterization of the various MEN-2 associated phenotypes (familial medullary thyroid cancer, multiple endocrine neoplasia 2A and 2B) evolved at the bedside, it was at the bench where the underlying RET (REarranged during Transfection) germline mutations were identified. Molecular information has revolutionized our understanding and continues to transform the clinical management of this...

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Source

Identifiers

PMID: 16343738
DOI: 10.1016/j.mce.2005.10.028

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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