Article
Autosomal linkage analysis for the level of response to alcohol.
Alcoholism, clinical and experimental research - 1 Nov 2005
Schuckit Marc A, Wilhelmsen Kirk, Smith Tom L, Feiler Heidi S, Lind Penelope, Lange Leslie A, Kalmijn Jelger
Abstract excerpt
BACKGROUND: The level of response (LR) to alcohol is a genetically-influenced phenotype related to the alcoholism risk. Usually measured by evaluating psychological and physiological changes that follow the administration of alcohol, the heritability of LR is estimated to be between 0.4 and 0.6, and efforts are being made to find genes related to this phenotype. This paper presents data from a family-based genome...
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