Article
Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans.
Proceedings of the National Academy of Sciences of the United States of America - 23 Dec 2008
Joslyn Geoff, Brush Gerry, Robertson Margaret, Smith Tom L, Kalmijn Jelger, Schuckit Marc, White Raymond L
Abstract excerpt
As with other genetically complex common psychiatric and medical conditions, multiple genetic and environmental components contribute to alcohol use disorders (AUDs), which can confound attempts to identify genetic components. Intermediate phenotypes are often more closely correlated with underlying biology and have often proven invaluable in genetic studies. Level of response (LR) to alcohol is an intermediate...
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