Article
The search for genes related to a low-level response to alcohol determined by alcohol challenges.
Alcoholism, clinical and experimental research - 1 Jul 2003
Wilhelmsen Kirk C, Schuckit Marc, Smith Tom L, Lee James V, Segall Samantha K, Feiler Heidi S, Kalmijn Jelger
Abstract excerpt
BACKGROUND: A low level of response (LR) to alcohol seems to relate to a substantial proportion of the risk for alcoholism and to have significant heritability. METHODS: This report describes the results of a genome-wide segregation analysis for the first 139 pairs of full siblings by using an alcohol challenge protocol as a direct measure of LR. Subjects from 18 to 29 years old were selected if the original...
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