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Article

The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis.

Alcoholism, clinical and experimental research - 1 Jan 2011

Webb Amy, Lind Penelope A, Kalmijn Jelger, Feiler Heidi S, Smith Tom L, Schuckit Marc A, Wilhelmsen Kirk

Abstract excerpt

BACKGROUND: A low level of response to alcohol during an individual's early experience with alcohol is associated with an increase risk of alcoholism. A family-based genome-wide linkage analysis using sibling pairs that underwent an alcohol challenge where the level of response to alcohol was measured with the Subjective High Assessment Scale (SHAS) implicated the 10q terminal (10qter) region. CYP2E1, a gene...

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Identifiers

PMID: 20958328
DOI: 10.1111/j.1530-0277.2010.01317.x
PMCID: PMC3005010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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