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Article

Genetic dissection of the zebrafish retinal stem-cell compartment.

Developmental biology - 1 May 2005

Wehman Ann M, Staub Wendy, Meyers Jason R, Raymond Pamela A, Baier Herwig

Abstract excerpt

In a large-scale forward-genetic screen, we discovered that a limited number of genes are required for the regulation of retinal stem cells after embryogenesis in zebrafish. In 18 mutants out of almost 2000 F2 families screened, the eye undergoes normal embryonic development, but fails to continue growth from the ciliary marginal zone (CMZ), the post-embryonic stem-cell niche. Class I-A mutants (5 loci) display...

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Identifiers

PMID: 15848388
DOI: 10.1016/j.ydbio.2005.02.010

Genes

RPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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