Article
Genetic variation and quasi-species.
Current opinion in genetics & development - 1 Feb 1992
Domingo E
Abstract excerpt
During the past year the relative fitness, that is, overall replication ability, and the fitness gain of animal virus variants have been quantified, providing new insight into the dynamics for the generation of RNA virus quasi-species. Measurements of mutant frequencies and rates of genetic diversification have confirmed the extreme complexity of RNA virus and retrovirus populations.
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