Article
Ependymomas in infancy: underlying genetic alterations, histological features, and clinical outcome.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Nov 2020
Jünger Stephanie T, Andreiuolo Felipe, Mynarek Martin, Dörner Evelyn, Zur Mühlen Anja, Rutkowski Stefan, von Bueren Andre O, Pietsch Torsten
Abstract excerpt
INTRODUCTION: Young age is an adverse prognostic factor in children with ependymomas. Treatment of these infants is challenging since beneficial therapeutic options are limited. As ependymomas are considered a biologically heterogeneous group, we aimed to characterize infant ependymomas with regard to their histological and genetic features. MATERIALS AND METHODS: We analyzed 28 ependymomas occurring in children...
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