Article
The Impact of Concurrent and TreatedAncylostoma ceylanicumHookworm Infections on the Immunogenicity of a Recombinant Hookworm Vaccine in Hamsters
5 Dec 2005
Abstract excerpt
BACKGROUND: The effect of concurrent (active) and treated hookworm infections on the immunogenicity of vaccination with the recombinant fusion protein Ay-Ancylostoma-secreted protein 2 was analyzed in the Golden Syrian hamster. METHODS: Hamsters were infected with the hookworm Ancylostoma ceylanicum and vaccinated with the recombinant protein, with Quil A used as adjuvant. As controls, hookworm-infected hamsters...
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