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Article

Intraspecific epitopic variation in a carbohydrate antigen exposed on the surface of Trichostrongylus colubriformis infective L3 larvae.

PLoS pathogens - 1 Sept 2009

Maass David R, Harrison Gavin B, Grant Warwick N, Hein Wayne R, Shoemaker Charles B

Abstract excerpt

The carbohydrate larval antigen, CarLA, is present on the exposed surface of all strongylid nematode infective L3 larvae tested, and antibodies against CarLA can promote rapid immune rejection of incoming Trichostrongylus colubriformis larvae in sheep. A library of ovine recombinant single chain Fv (scFv) antibody fragments, displayed on phage, was prepared from B cell mRNA of field-immune sheep. Phage displaying...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19779563
DOI: 10.1371/journal.ppat.1000597
PMCID: PMC2742895

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Source receipt: pubmed, retrieved 7 Sept 2026.

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