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Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host’s immune system

2025-02-03

Abstract excerpt

Hookworms are intestinal parasitic nematodes that chronically infect ∼500 million people, with reinfection common even after clearance by drugs. How infecting hookworms successfully overcome host protective mechanisms is unclear, but it may involve hookworm proteins that digest host tissues, or counteract the host’s immune system, or both. To find such proteins in the zoonotic hookworm Ancylostoma ceylanicum , we...

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Literature Corpus work
43877574-788c-5709-afb1-ec2e71f8286e
DOI
10.1101/2025.02.01.636063
Open publication

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Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host’s immune systemDOI 10.1101/2025.02.01.636063
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