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Article

Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays.

The Journal of clinical investigation - 1 Dec 2005

Li Quan-Zhen, Zhen Quan Li, Xie Chun, Wu Tianfu, Mackay Meggan, Aranow Cynthia, Putterman Chaim, Mohan Chandra

Abstract excerpt

Nephrophilic autoantibodies dominate the seroprofile in lupus, but their fine specificities remain ill defined. We constructed a multiplexed proteome microarray bearing about 30 antigens known to be expressed in the glomerular milieu and used it to study serum autoantibodies in lupus. Compared with normal serum, serum from B6.Sle1.lpr lupus mice (C57BL/6 mice homozygous for the NZM2410/NZW allele of Sle1 as well...

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PMID: 16322790
DOI: 10.1172/JCI23587
PMCID: PMC1297234

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FAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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