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Article

Autoantibody Profiling in Multiple Sclerosis Using Arrays of Human Protein Fragments

3 Jun 2013

Abstract excerpt

Profiling the autoantibody repertoire with large antigen collections is emerging as a powerful tool for the identification of biomarkers for autoimmune diseases. Here, a systematic and undirected approach was taken to screen for profiles of IgG in human plasma from 90 individuals with multiple sclerosis related diagnoses. Reactivity pattern of 11,520 protein fragments (representing ∼38% of all human protein...

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PMID: 23732997
DOI: 10.1074/mcp.m112.026757

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