Article
Increased risk of ovarian cancer in integrin beta3 Leu33Pro homozygotes.
Endocrine-related cancer - 1 Dec 2005
Bojesen S E, Kjaer S K, Høgdall E V S, Thomsen B L, Høgdall C K, Blaakaer J, Tybjaerg-Hansen A, Nordestgaard B G
Abstract excerpt
We previously demonstrated that integrin beta(3) Leu33Pro homozygotes have an increased risk of cancer, possibly most pronounced for ovarian cancer. We now test the latter hypothesis in case-control and prospective studies. We genotyped 463 Danish women with ovarian cancer, and 4291 women from the Danish general population. Calculation of odds ratios by conditional logistic regression was performed in the...
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