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Article

Breast cancer susceptibility variants alter risk in familial ovarian cancer.

Familial cancer - 1 Dec 2010

Latif A, McBurney H J, Roberts S A, Lalloo F, Howell A, Evans D G, Newman W G

Abstract excerpt

Recent candidate gene and genome wide association studies have revealed novel loci associated with an increased risk of breast cancer. We evaluated the effect of these breast cancer associated variants on ovarian cancer risk in individuals with familial ovarian cancer both with and without BRCA1 or BRCA2 mutations. A total of 158 unrelated white British women (54 BRCA1/2 mutation positive and 104 BRCA1/2 mutation...

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Source

Identifiers

PMID: 20502973
DOI: 10.1007/s10689-010-9349-2

Genes

BRCA1
CASP8
TOX3
BRCA2
FGFR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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