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Article

Mouse models of transforming growth factor β impact in breast development and cancer

1 Dec 2005

Abstract excerpt

It is now recognized that transforming growth factor beta (TGF-beta) is an important factor that regulates normal breast development as well as breast cancer. Genetically engineered mouse models have been used to determine the role and mechanism of TGF-beta action in normal development and diseases of the breast. Using these models, it has been determined that TGF-beta regulates many steps of normal mammary gland...

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PMID: 16322320
DOI: 10.1677/erc.1.00936

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Source receipt: pubmed, retrieved 7 Sept 2026.

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