Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p.

The Journal of biological chemistry - 3 Feb 2006

Polevoda Bogdan, Span Lisa, Sherman Fred

Abstract excerpt

The translation release factors (RFs) RF1 and RF2 of Escherichia coli are methylated at the N5-glutamine of the GGQ motif by PrmC methyltransferase. This motif is conserved in organisms from bacteria to higher eukaryotes. The Saccharomyces cerevisiae RFs, mitochondrial Mrf1p and cytoplasmic Sup45p (eRF1), have sequence similarities to the bacterial RFs, including the potential site of glutamine methylation in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methyltransferases

Share to Microtubule-Associated Proteins

Share to Mitochondrial Proteins

Share to Peptide Termination Factors

Share to Saccharomyces cerevisiae Proteins

Share to Sequence Deletion

Source

Identifiers

PMID: 16321977
DOI: 10.1074/jbc.M507651200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p.PMID 16321977Read ↗

Deficiency in a glutamine-specific methyltransferase for release factor causes mouse embryonic lethality.Semantic proximity Read ↗

Mammalian HEMK1 Methylates Glutamine Residue of the GGQ Motif of Mitochondrial Release FactorsSemantic proximity Read ↗

The yeast nuclear gene MRF1 encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects.Semantic proximity Read ↗

The yeast GTPase Mtg2p is required for mitochondrial translation and partially suppresses an rRNA methyltransferase mutant, mrm2.Semantic proximity Read ↗

Mitochondrial release factor in yeast: interplay of functional domains.Semantic proximity Read ↗

The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases.Semantic proximity Read ↗

Evolution and diversification of the organellar release factor family.Semantic proximity Read ↗

NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein.Semantic proximity Read ↗

Trm112p is a 15-kDa zinc finger protein essential for the activity of two tRNA and one protein methyltransferases in yeast.Semantic proximity Read ↗

Yeast m6A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment.Semantic proximity Read ↗

The ribosomal l1 protuberance in yeast is methylated on a lysine residue catalyzed by a seven-beta-strand methyltransferase.Semantic proximity Read ↗

Functional characterization of the YmcB and YqeV tRNA methylthiotransferases of Bacillus subtilis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.