Article
[Contribution of MODY6 gene in the pathogenesis of familial type 2 diabetes in Chinese population].
Zhonghua yi xue za zhi - 14 Sept 2005
Han Xue-yao, Liu Chun-yan, Ji Li-nong
Abstract excerpt
OBJECTIVE: To investigate the contribution of MODY6 gene in the pathogenesis of familiar type 2 diabetes in Chinese population. METHODS: PCR and single strand configuration polymorphism (PCR-SSCP) technique was used to screen the coding sequence of NeuroD1/BETA2 gene for DNA variants in 188 probands in the pedigrees of familiar type 2 diabetes and 130 normal persons as controls in Beijing, China. The discovered...
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