Article
[The association of two single nucleotide polymorphisms in PRKCZ and UTS2 respectively with type 2 diabetes in Han people of northern China].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Jun 2002
Sun Hong-xia, Du Wei-nan, Zuo Jin, Wu Guo-dong, Shi Gui-bin, Shen Yan, Qiang Bo-qin, Yao Zhi-jian, Hang Jian-mei, Wang Heng, Huang Wei, Chen Zhu, Fang Fu-de
Abstract excerpt
OBJECTIVE: To probe the candidate susceptibility gene (s) of type 2 diabetes in the formal mapping region, 1p36.33-p36.23, in Han people of Northern China using single nucleotide polymorphisms (SNPs). METHODS: 23 SNPs located in 10 candidate genes in the mapping region were chosen from public SNP domain by bioinformatic methods and single base extension (SBE) method were used to genotype the loci in 192 sporadic...
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