Article
[Association of polymorphism in neurogenic differentiation factor 1 gene with type 2 diabetes].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2002
Ye Linxiu, Xu Yancheng, Zhu Yilian, Fan Youyun, Deng Haohua, Zhang Junxia
Abstract excerpt
OBJECTIVE: To evaluate the role of polymorphism in the neurogenic differentiation factor 1(Neuro D) gene in Chinese patients with type 2 diabetes mellitus. METHODS: The genotypes of codon 45 variant (GCC-->ACC) in the Neuro D gene were determined by mismatch PCR-restriction fragment length polymorphism assay in 448 Chinese, including 124 subjects with normal glucose tolerance and 324 patients with type 2 diabetes...
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