Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ala45Thr variation in neuroD1 gene is associated with early-onset type 2 diabetes with or without diabetic pedigree in Chinese.

Molecular and cellular biochemistry - 1 Oct 2006

Liu Limei, Jia Weiping, Zheng Taishan, Li Ming, Lu Huijuan, Xiang Kunsan

Abstract excerpt

OBJECTIVE: Based on onset-age stratified analysis may be useful to determine the association of NeuroD1-Ala45Thr variation with susceptibility to genetic heterogeneous type 2 diabetes mellitus (T2DM), we investigated the Ala45Thr variation in unrelated early-onset and late-onset T2DM with or without diabetic pedigree and unrelated non-diabetic control subjects in Chinese. METHODS: 175 early-onset and 194...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alanine
Share to Amino Acid Substitution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Basic Helix-Loop-Helix Transcription Factors

Share to Case-Control Studies

Share to Diabetes Mellitus, Type 2

Share to Pedigree

Share to Threonine

Source

Identifiers

PMID: 16773428
DOI: 10.1007/s11010-006-9217-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ala45Thr variation in neuroD1 gene is associated with early-onset type 2 diabetes with or without diabetic pedigree in Chinese.PMID 16773428Read ↗

Neuronal Differentiation 1 gene Ala45Thr polymorphism and type 2 diabetes mellitus: A meta-analysis of 7,940 subjects.Semantic proximity Read ↗

Evaluation of variant A45T in NEUROD1/BETA2 for its association with type 2 diabetes mellitus.Semantic proximity Read ↗

Identification of nucleotide polymorphism within the NeuroD1 candidate gene and its association with type 1 diabetes susceptibility in Iranian people by polymerase chain reaction-restriction fragment length polymorphism.Semantic proximity Read ↗

The association of Ala45Thr polymorphism in NeuroD with child-onset Type 1a diabetes in Japanese.Semantic proximity Read ↗

[Association of polymorphism in neurogenic differentiation factor 1 gene with type 2 diabetes].Semantic proximity Read ↗

Ala45Thr polymorphism of the NEUROD1 gene and diabetes susceptibility: a meta-analysis.Semantic proximity Read ↗

Rs2227982 and rs2227981 in PDCD1 gene are functional SNPs associated with T1D risk in East Asian.Semantic proximity Read ↗

CDKAL1 gene rs7756992 A/G polymorphism and type 2 diabetes mellitus: a meta-analysis of 62,567 subjects.Semantic proximity Read ↗

Lack of association of the Ala45Thr variant in the BETA2/NEUROD1 with type 1 diabetes in Japanese.Semantic proximity Read ↗

[Distribution of the diabetes related gene variants among Chinese population born in early 1960s].Semantic proximity Read ↗

GLP1R Rs3765467 Polymorphism Is Associated With The Risk Of Early-Onset Type 2 DiabetesSemantic proximity Read ↗

Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.