Article
[Molecular scanning of MODY1 gene mutations in pedigrees of early onset type 2 diabetes in Beijing].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Sept 2006
Jia He-tang, Zhang Su-hua, Ji Li-nong, Han Xue-yao
Abstract excerpt
OBJECTIVE: To explore MDOY1 gene mutations in pedigrees of early-onset familial type 2 diabetes. METHODS: We collected 100 early-onset type 2 diabetes pedigrees in Beijing, in which the probands were diagnosed with type 2 diabetes before the age of 40 years with at least one first-degree relative having such a diagnosis before the age of 45 years. PCR was employed to amplify all the exons and exon/intron splice...
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