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Article

Regulation of G0 entry by the Pho80-Pho85 cyclin-CDK complex.

The EMBO journal - 21 Dec 2005

Wanke Valeria, Pedruzzi Ivo, Cameroni Elisabetta, Dubouloz Frédérique, De Virgilio Claudio

Abstract excerpt

Eukaryotic cell proliferation is controlled by growth factors and essential nutrients. In their absence, cells may enter into a quiescent state (G0). In Saccharomyces cerevisiae, the conserved protein kinase A (PKA) and rapamycin-sensitive TOR (TORC1) pathways antagonize G0 entry in response to carbon and/or nitrogen availability primarily by inhibiting the PAS kinase Rim15 function. Here, we show that the...

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Identifiers

PMID: 16308562
DOI: 10.1038/sj.emboj.7600889
PMCID: PMC1356330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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