Article
To divide or not to divide: a key role of Rim15 in calorie-restricted yeast cultures.
Biochimica et biophysica acta - 1 May 2014
Bisschops Markus M M, Zwartjens Priscilla, Keuter Sebastiaan G F, Pronk Jack T, Daran-Lapujade Pascale
Abstract excerpt
The PAS kinase Rim15 is proposed to integrate signals from different nutrient-sensing pathways and to control transcriptional reprogramming of Saccharomyces cerevisiae upon nutrient depletion. Despite this proposed role, previous transcriptome analyses of rim15 mutants solely focused on growing cultures. In the present work, retentostat cultivation enabled analysis of the role of Rim15 under severely...
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