Article
CDKN2A mutations in Scottish families with cutaneous melanoma: results from 32 newly identified families.
The British journal of dermatology - 1 Dec 2005
Lang J, Boxer M, MacKie R M
Abstract excerpt
BACKGROUND: Up to 5% of patients with melanoma have a family history of a first-degree relative also being affected. OBJECTIVES: To study such families for germline mutations, to help clarify the gene-environment interaction in melanoma aetiology. METHODS: Thirty-two families in Scotland with melanoma in two or more first-degree relatives are reported for the first time. Peripheral blood DNA was extracted, and...
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