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Article

CDKN2A germ-line mutations in individuals with multiple cutaneous melanomas.

Cancer research - 15 Dec 2000

Hashemi J, Platz A, Ueno T, Stierner U, Ringborg U, Hansson J

Abstract excerpt

Germ-line CDKN2A mutations are present in some kindreds with hereditary cutaneous melanoma, and in Sweden a founder mutation with an extra arginine in codon 113 (113insR) has been identified. We screened 80 individuals with at least two primary cutaneous melanomas, who were identified mainly by a search of a regional cancer registry, for germ-line CDKN2A mutations. In nine patients, CDKN2A alterations that may...

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PMID: 11156381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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