Article
Genetic variation in bactericidal/permeability-increasing protein influences the risk of developing rapid airflow decline after hematopoietic cell transplantation.
Blood - 1 Mar 2006
Chien Jason W, Zhao Lue Ping, Hansen John A, Fan Wen Hong, Parimon Tanyalak, Clark Joan G
Abstract excerpt
Innate immunity is involved in the biology of graft versus host disease and common airway diseases. We screened 15 genes in this pathway using a linkage disequilibrium-based approach to identify potential candidate genes that may be involved in the development of airflow obstruction after hematopoietic cell transplantation. Sixty-nine single-nucleotide polymorphisms were selected for assessment in a discovery...
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