Article
Calcium oscillations in type-1 astrocytes, the effect of a presenilin 1 (PS1) mutation.
Neuroscience letters - 6 Mar 2006
Johnston Jane M, Burnett Paul, Thomas Andrew P, Tezapsidis Nikolaos
Abstract excerpt
Stimulation of type-1 astrocytes, by a number of agonists, has been shown to increase cytosolic Ca2+ concentrations in an oscillatory manner. However, it is unknown how these are driven or altered by aging, injury or disease. Therefore, we characterized the signaling properties of rat type-1 astrocytes in monolayer cultures. Ca2+ responses were recorded in astrocytes stimulated with ATP or glutamate. Oscillations...
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