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speck, First Identified in Drosophila melanogaster in 1910, Is Encoded by the Arylalkalamine N-Acetyltransferase (AANAT1) Gene.

G3 (Bethesda, Md.) - 2 Sept 2020

Spana Eric P, Abrams Amanda B, Ellis Katharine T, Klein Jason C, Ruderman Brandon T, Shi Alvin H, Zhu Daniel, Stewart Andrea, May Susan

Abstract excerpt

The pigmentation mutation speck is a commonly used recombination marker characterized by a darkly pigmented region at the wing hinge. Identified in 1910 by Thomas Hunt Morgan, speck was characterized by Sturtevant as the most "workable" mutant in the rightmost region of the second chromosome and eventually localized to 2-107.0 and 60C1-2. Though the first speck mutation was isolated over 110 years ago, speck is...

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PMID: 32709620
DOI: 10.1534/g3.120.401470
PMCID: PMC7466976

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