Article
tan and ebony genes regulate a novel pathway for transmitter metabolism at fly photoreceptor terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Dec 2002
Borycz Janusz, Borycz Jolanta A, Loubani Mohammed, Meinertzhagen Ian A
Abstract excerpt
In Drosophila melanogaster, ebony and tan, two cuticle melanizing mutants, regulate the conjugation (ebony) of beta-alanine to dopamine or hydrolysis (tan) of the beta-alanyl conjugate to liberate dopamine. beta-alanine biosynthesis is regulated by black. ebony and tan also exert unexplained reciprocal defects in the electroretinogram, at ON and OFF transients attributable to impaired transmission at...
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