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Article

The four aldehyde oxidases of Drosophila melanogaster have different gene expression patterns and enzyme substrate specificities.

The Journal of experimental biology - 15 Jun 2014

Marelja Zvonimir, Dambowsky Miriam, Bolis Marco, Georgiou Marina L, Garattini Enrico, Missirlis Fanis, Leimkühler Silke

Abstract excerpt

In the genome of Drosophila melanogaster, four genes coding for aldehyde oxidases (AOX1-4) were identified on chromosome 3. Phylogenetic analysis showed that the AOX gene cluster evolved via independent duplication events in the vertebrate and invertebrate lineages. The functional role and the substrate specificity of the distinct Drosophila AOX enzymes is unknown. Two loss-of-function mutant alleles in this gene...

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Source

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Identifiers

PMID: 24737760
DOI: 10.1242/jeb.102129
PMCID: PMC4055135

Genes

AOX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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