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Article

Association of CAT polymorphisms with catalase activity and exposure to environmental oxidative stimuli.

Free radical research - 1 Dec 2005

Nadif Rachel, Mintz Margaret, Jedlicka Anne, Bertrand Jean-Pierre, Kleeberger Steven R, Kauffmann Francine

Abstract excerpt

We tested the hypotheses that catalase activity is modified by CAT single nucleotide polymorphisms (SNPs) (-262;-844), and by their interactions with oxidant exposures (coal dusts, smoking), lymphotoxin alpha (LTA, NcoI) and tumor necrosis factor (TNF, -308) in 196 miners. Erythrocyte catalase, superoxide dismutase, and glutathione peroxidase activities were measured. The CAT -262 SNP was related to lower...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16298864
DOI: 10.1080/10715760500306711
PMCID: PMC1877822

Genes

CAT
LTA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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