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Article

Polymorphisms and functional activity in superoxide dismutase and catalase genes in smokers with COPD.

The European respiratory journal - 1 Oct 2007

Mak J C W, Ho S P, Yu W C, Choo K L, Chu C M, Yew W W, Lam W K, Chan-Yeung M

Abstract excerpt

Increased oxidative stress has been implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). This study investigated the risk of COPD and the substitution of alanine 16 with valine (Ala16Val) polymorphism of manganese-superoxide dismutase (Mn-SOD) and the cytosine to thymidine transition of nucleotide -262 (-262C>T) polymorphism of the catalase gene, and the activity of erythrocyte SOD and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17567676
DOI: 10.1183/09031936.00015207

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