Article
Interaction between single nucleotide polymorphism in catalase gene and catalase activity under the conditions of oxidative stress.
Physiological research - 1 Jan 2012
Komina A V, Korostileva K A, Gyrylova S N, Belonogov R N, Ruksha T G
Abstract excerpt
Catalase is an antioxidant enzyme the activity of which is crucial for the protection against damage caused by reactive oxygen species. The -262C>T polymorphism in the promoter region of catalase gene was found to be associated with altered catalase levels. In this study, peripheral blood mononuclear cells catalase activity was measured after H(2)O(2)-induced oxidative stress. C/T and T/T genotypes were...
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