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Significance of viral load, core promoter/precore mutations and specific sequences of polymerase gene in HBV-infected patients on 3-year lamivudine treatment.

Antiviral therapy - 1 Jan 2006

Yuen Man-Fung, Sablon Erwin, Libbrecht Evelien, Van De Velde Hilde, Wong Danny Ka-Ho, Fung James, Wong Benjamin Chun-Yu, Lai Ching-Lung

Abstract excerpt

BACKGROUND: Comprehensive study on viral factors predicting treatment responsiveness to lamivudine is lacking. AIMS: To define the significance of various viral factors and changes of viral population with lamivudine treatment. PATIENTS AND METHODS: Hepatitis B virus (HBV) DNA levels at baseline, week 24, 52 and year 3 were measured in 80 patients on continuous lamivudine therapy for 3 years. Genotypes, core...

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PMID: 17310822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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