Article
Multipoint linkage disequilibrium mapping using case-control designs.
Genetic epidemiology - 1 Dec 2005
Liang Kung-Yee, Chiu Yen-Feng
Abstract excerpt
Case-control study has been and continues to be one of the most popular designs in epidemiology. More recently, this design has been adopted to test for candidate genes when searching for disease genetic etiology. In this report, we present a multipoint linkage disequilibrium (LD) mapping approach with the focus on estimating the location of the target trait locus. It builds upon a representation, which shows...
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