Construction and characterization of Streptomyces coelicolor A3(2) mutants that are multiply deficient in the nonessential hrd-encoded RNA polymerase sigma factors.

doi:10.1128/jb.174.15.5165-5167.1992

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Article

Construction and characterization of Streptomyces coelicolor A3(2) mutants that are multiply deficient in the nonessential hrd-encoded RNA polymerase sigma factors.

Journal of bacteriology - 1 Aug 1992

Buttner M J, Lewis C G

Abstract excerpt

Previous studies showed that Streptomyces coelicolor A3(2) has four genes (hrdA, hrdB, hrdC, and hrdD) that appear to encode RNA polymerase sigma factors very similar to the sigma 70 subunit of Escherichia coli and that hrdC and hrdD could be individually disrupted without causing obvious phenoty...

Topics

Alleles
Cloning, Molecular
Genes, Bacterial
Mutation
Sigma Factor
Streptomyces

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