Article
BldD from Streptomyces coelicolor is a non-essential global regulator that binds its own promoter as a dimer.
FEMS microbiology letters - 8 Aug 2003
Elliot Marie A, Locke Troy R, Galibois Claire M, Leskiw Brenda K
Abstract excerpt
We have shown that the bldD gene of Streptomyces coelicolor, while required for antibiotic production and morphological differentiation, is not essential for viability. We have also demonstrated that BldD forms a higher order complex both in solution and when bound to target DNA. Purified BldD exists in three forms in solution, as a tetramer, dimer and monomer, but only in the dimeric form when bound to its own...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.