Article
Directing Differentiation of Pluripotent Stem Cells Toward Retinal Pigment Epithelium Lineage.
Stem cells translational medicine - 1 Feb 2017
Choudhary Parul, Booth Heather, Gutteridge Alex, Surmacz Beata, Louca Irene, Steer Juliette, Kerby Julie, Whiting Paul John
Abstract excerpt
Development of efficient and reproducible conditions for directed differentiation of pluripotent stem cells into specific cell types is important not only to understand early human development but also to enable more practical applications, such as in vitro disease modeling, drug discovery, and cell therapies. The differentiation of stem cells to retinal pigment epithelium (RPE) in particular holds promise as a...
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