Article
Histone H3 Ser10 phosphorylation-independent function of Snf1 and Reg1 proteins rescues a gcn5- mutant in HIS3 expression.
Molecular and cellular biology - 1 Dec 2005
Liu Yang, Xu Xinjing, Singh-Rodriguez Soumya, Zhao Yan, Kuo Min-Hao
Abstract excerpt
Gcn5 protein is a prototypical histone acetyltransferase that controls transcription of multiple yeast genes. To identify molecular functions that act downstream of or in parallel with Gcn5 protein, we screened for suppressors that rescue the transcriptional defects of HIS3 caused by a catalytically inactive mutant Gcn5, the E173H mutant. One bypass of Gcn5 requirement gene (BGR) suppressor was mapped to the REG1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
